|
|
(S)-3-methyl-2-oxopentanoate + L-valine <=> L-isoleucine + 2-oxoisovalerate
|
2.6.1.32
valine---3-methyl-2-oxovalerate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
|
–
–
|
|
| |
BRENDA:
BR47684;
BS356527
KEGG:
R02200
MetaCyc:
2.6.1.32-RXN
SABIO-RK:
2173
|
|
|
|
H+ + (S)-3-methyl-2-oxopentanoate <=> 2-methylbutanal + CO2
|
4.1.1.1
pyruvate decarboxylase
4.1.1.7
benzoylformate decarboxylase
4.1.1.72
branched-chain-2-oxoacid decarboxylase
|
–
–
–
|
M
|
| |
BRENDA:
BR48316;
BS370627
KEGG:
R03894
MetaCyc:
4.1.1.72-RXN
|
|
|
|
L-isoleucine + H2O + NAD+ <=> NH3 + (S)-3-methyl-2-oxopentanoate + NADH + H+
|
1.4.1.1
alanine dehydrogenase
1.4.1.2
glutamate dehydrogenase
1.4.1.20
phenylalanine dehydrogenase
1.4.1.23
valine dehydrogenase (NAD+)
1.4.1.5
L-amino-acid dehydrogenase
1.4.1.8
valine dehydrogenase (NADP+)
1.4.1.9
leucine dehydrogenase
|
–
–
–
–
–
–
–
|
K
|
| |
BRENDA:
BS232308
KEGG:
R02196
MetaCyc:
ILEDEAMINE-RXN
SABIO-RK:
7740
|
|
|
|
L-isoleucine + 2-oxoglutarate <=> L-glutamate + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.67
2-aminohexanoate transaminase
|
–
–
|
BMK
|
| |
BRENDA:
BS356522;
BS452227
KEGG:
R02199
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERILEU-RXN
SABIO-RK:
2171;
9086
|
|
|
|
2R,3R-2,3-dihydroxy-3-methylpentanoate <=> (S)-3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
MK
|
| |
BRENDA:
BS453486
KEGG:
R05070
MetaCyc:
DIHYDROXYMETVALDEHYDRAT-RXN
|
|
|
|
(S)-3-methyl-2-oxopentanoate + NAD+ + CoA <=> (S)-2-methylbutanoyl-CoA + NADH + CO2
|
1.2.1.25
branched-chain alpha-keto acid dehydrogenase system
|
–
|
M
|
| |
KEGG:
R03171
MetaCyc:
2KETO-3METHYLVALERATE-RXN
|
|
|
|
(S)-3-methyl-2-oxopentanoate + CoA + oxidized_ferredoxin <=> (S)-2-methylbutanoyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
|
–
|
MK
|
| |
KEGG:
R08567
MetaCyc:
RXN-19503
|
|
|
|
L-isoleucine + H2O + O2 <=> (S)-3-methyl-2-oxopentanoate + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
K
|
| |
KEGG:
R02197
|
|
|
|
(S)-3-methyl-2-oxopentanoate + Enzyme_N6-(lipoyl)lysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
K
|
| |
KEGG:
R04225
|
|
|
|
(S)-3-methyl-2-oxopentanoate + thiamine_diphosphate <=> 2-Methyl-1-hydroxybutyl-ThPP + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
K
|
| |
KEGG:
R07603
|
|
|
|
(S)-3-methyl-2-oxopentanoate + [apo_BCAA_dehydrogenase_E2_protein]_N6-lipoyl-L-lysine + H+ <=> [apo_BCAA_dehydrogenase_E2_protein]_N6-S-[2-methylbutanoyl]dihydrolipoyl-L-lysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
| |
MetaCyc:
METHYLVALERATE-RXN
|
|
|
|
(S)-3-methyl-2-oxopentanoate + reduced_methyl_viologen <=> 2-hydroxy-3-methylpentanoate + methyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
| |
BRENDA:
BS371410
|
|
|
|
(S)-3-methyl-2-oxopentanoate + reduced_benzyl_viologen <=> 2-hydroxy-3-methylpentanoate + Oxidized_benzyl_viologen
|
1.1.99.30
2-oxo-acid reductase
|
–
|
|
| |
BRENDA:
BS371409
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-isoleucine <=> L-methionine + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
| |
SABIO-RK:
12603
|
|
